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Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome
In eukaryotes, accurate chromosome segregation in mitosis and meiosis maintains genome stability and prevents aneuploidy. Kinetochores are large protein complexes, that by assembling onto specialized Cenp-A nucleosomes (1,2), function to connect centromeric chromatin to microtubules of the mitotic s...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859074/ https://ncbi.nlm.nih.gov/pubmed/31578520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1609-1 |
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