Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers

Our aim was to investigate the patterns and trajectories of white matter (WM) diffusion abnormalities in microtubule-associated protein tau (MAPT) mutations carriers. We studied 22 MAPT mutation carriers (12 asymptomatic, 10 symptomatic) and 20 noncarriers from 8 families, who underwent diffusion te...

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Publicado no:Neurobiol Aging
Main Authors: Chen, Qin, Boeve, Bradley F., Schwarz, Christopher G., Reid, Robert, Tosakulwong, Nirubol, Lesnick, Timothy G., Bove, Jessica, Brannelly, Patrick, Brushaber, Danielle, Coppola, Giovanni, Dheel, Christina, Dickerson, Bradford C., Dickinson, Susan, Faber, Kelley, Fields, Julie, Fong, Jamie, Foroud, Tatiana, Forsberg, Leah, Gavrilova, Ralitza H., Gearhart, Debra, Ghoshal, Nupur, Goldman, Jill, Graff-Radford, Jonathan, Graff-Radford, Neill R., Grossman, Murray, Haley, Dana, Heuer, Hilary W., Hsiung, Ging-Yuek R., Huey, Edward, Irwin, David J., Jack, Clifford R., Jones, David T., Jones, Lynne, Karydas, Anna M., Knopman, David S., Kornak, John, Kramer, Joel, Kremers, Walter, Kukull, Walter A., Lapid, Maria, Lucente, Diane, Lungu, Codrin, Mackenzie, Ian R.A., Manoochehri, Masood, McGinnis, Scott, Miller, Bruce L., Pearlman, Rodney, Petrucelli, Leonard, Potter, Madeline, Rademakers, Rosa, Ramos, Eliana M., Rankin, Katherine P., Rascovsky, Katya, Sengdy, Pheth, Shaw, Leslie, Syrjanen, Jeremy, Tatton, Nadine, Taylor, Joanne, Toga, Arthur W., Trojanowski, John, Weintraub, Sandra, Wong, Bonnie, Boxer, Adam L., Rosen, Howie, Wszolek, Zbigniew, Kantarci, Kejal
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858933/
https://ncbi.nlm.nih.gov/pubmed/31585367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.08.011
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