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Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

Modification of specific Ser and Thr residues of nucleocytoplasmic proteins with O-GlcNAc, catalyzed by O-GlcNAc transferase (OGT), is an abundant post-translational event essential for proper animal development and dysregulated in various diseases. Due to the rapid concurrent removal by the single...

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Gorelik, Andrii, Galan Bartual, Sergio, Borodkin, Vladimir S., Varghese, Joby, Ferenbach, Andrew T., van Aalten, Daan M. F.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858883/
https://ncbi.nlm.nih.gov/pubmed/31695185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0325-8
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