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Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells
BACKGROUND: As the precursors of sperm and eggs, human primordial germ cells (hPGCs) emerge as early as weeks 2 to 3 of post-implantation development. Recently, robust hPGC induction models have been established in vitro with different protocols, but global 5mC/5hmC epigenetic reprogramming is not i...
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| Veröffentlicht in: | Stem Cell Res Ther |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858754/ https://ncbi.nlm.nih.gov/pubmed/31730021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1427-2 |
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