Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy bodies (LBs) c...

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Spremljeno u:
Bibliografski detalji
Izdano u:Acta Neuropathol Commun
Glavni autori: Henderson, Michael X., Sengupta, Medha, Trojanowski, John Q., Lee, Virginia M. Y.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858668/
https://ncbi.nlm.nih.gov/pubmed/31733655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0836-x
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