Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy bodies (LBs) c...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Henderson, Michael X., Sengupta, Medha, Trojanowski, John Q., Lee, Virginia M. Y.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858668/
https://ncbi.nlm.nih.gov/pubmed/31733655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0836-x
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