Pharmacokinetics of Azithromycin, Levofloxacin, and Ofloxacin in Rabbit Extraocular Tissues After Ophthalmic Administration

INTRODUCTION: Azithromycin demonstrates high tissue distribution and prolonged elimination half-life. In this study, we monitored the pharmacokinetics of a single ophthalmic administration of 1% azithromycin ophthalmic solution containing polycarbophil in the extraocular tissues, including the eyeli...

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Publicat a:Ophthalmol Ther
Autors principals: Sakai, Tatsuya, Shinno, Keisuke, Kurata, Masaaki, Kawamura, Akio
Format: Artigo
Idioma:Inglês
Publicat: Springer Healthcare 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858417/
https://ncbi.nlm.nih.gov/pubmed/31372937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40123-019-00205-0
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