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Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

INTRODUCTION: Brimonidine bioavailability in the aqueous humor depends on the solution pH following topical administration. The purpose of this study was to investigate the effect of solution pH on brimonidine distribution in the posterior ocular tissues in pigmented rabbits. METHODS: The anterior r...

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Bibliografische gegevens
Gepubliceerd in:Ophthalmol Ther
Hoofdauteurs: Shinno, Keisuke, Kurokawa, Kazuya, Kozai, Seiko, Kawamura, Akio, Inada, Katsuhiro, Tokushige, Hideki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Healthcare 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514203/
https://ncbi.nlm.nih.gov/pubmed/30891685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40123-019-0180-z
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