Ocular and Systemic Pharmacokinetics of Brimonidine and Timolol After Topical Administration in Rabbits: Comparison Between Fixed-Combination and Single Drugs

INTRODUCTION: This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and 0.5% timolol and single drugs (0.1% brimonidine tartrate...

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Vydáno v:Ophthalmol Ther
Hlavní autoři: Suzuki, Gen, Kunikane, Eriko, Shinno, Keisuke, Kozai, Seiko, Kurata, Masaaki, Kawamura, Akio
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Healthcare 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054494/
https://ncbi.nlm.nih.gov/pubmed/31953739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40123-020-00229-x
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