PTBP1-mediated regulation of AXL mRNA stability plays a role in lung tumorigenesis

AXL is expressed in many types of cancer and promotes cancer cell survival, metastasis and drug resistance. Here, we focus on identifying modulators that regulate AXL at the mRNA level. We have previously observed that the AXL promoter activity is inversely correlated with the AXL expression levels,...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Cho, Chun-Yu, Chung, Shih-Ying, Lin, Shankung, Huang, Jhy-Shrian, Chen, Yen-Lin, Jiang, Shih-Sheng, Cheng, Li-Chun, Kuo, Tsu-Hsiang, Lay, Jong-Ding, Yang, Ya-Yu, Lai, Gi-Ming, Chuang, Shuang-En
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858377/
https://ncbi.nlm.nih.gov/pubmed/31729427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53097-2
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