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AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

BACKGROUND: TNS2 is a focal adhesions protein and a binding partner for many proteins, including the receptor tyrosine kinase Axl. Although TNS2 can bind with Axl, the details of their interactions have not been elucidated. TNS2 is involved in IRS-1 signaling pathway. In this study, we confirmed the...

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Pubblicato in:J Biomed Sci
Autori principali: Cheng, Li-Chun, Chen, Yen-Lin, Cheng, An-Ning, Lee, Alan Yueh-Luen, Cho, Chun-Yu, Huang, Jhy-Shrian, Chuang, Shuang-En
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233515/
https://ncbi.nlm.nih.gov/pubmed/30419905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-018-0465-x
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