Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

Chronic inflammation and chromosome aneuploidy are major traits of primary liver cancer (PLC), which represent the second most common cause of cancer-related death worldwide. Increased cancer fitness and aggressiveness of PLC may be achieved by enhancing tumoral genomic complexity that alters tumor...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kwon, So Mee, Budhu, Anuradha, Woo, Hyun Goo, Chaisaingmongkol, Jittiporn, Dang, Hien, Forgues, Marshonna, Harris, Curtis C., Zhang, Gao, Auslander, Noam, Ruppin, Eytan, Mahidol, Chulabhorn, Ruchirawat, Mathuros, Wang, Xin Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858353/
https://ncbi.nlm.nih.gov/pubmed/31729408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52578-8
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