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A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

Disrupted regulation of cellular processes is considered one of the hallmarks of cancer. We analyze metabolomic and transcriptomic profiles jointly collected from breast cancer and hepatocellular carcinoma patients to explore the associations between the expression of metabolic enzymes and the level...

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Pubblicato in:Sci Rep
Autori principali: Auslander, Noam, Yizhak, Keren, Weinstock, Adam, Budhu, Anuradha, Tang, Wei, Wang, Xin Wei, Ambs, Stefan, Ruppin, Eytan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942812/
https://ncbi.nlm.nih.gov/pubmed/27406679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29662
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