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A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

Disrupted regulation of cellular processes is considered one of the hallmarks of cancer. We analyze metabolomic and transcriptomic profiles jointly collected from breast cancer and hepatocellular carcinoma patients to explore the associations between the expression of metabolic enzymes and the level...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Auslander, Noam, Yizhak, Keren, Weinstock, Adam, Budhu, Anuradha, Tang, Wei, Wang, Xin Wei, Ambs, Stefan, Ruppin, Eytan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942812/
https://ncbi.nlm.nih.gov/pubmed/27406679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29662
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