Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma

T-cell exhaustion denotes a hypofunctional state of T lymphocytes commonly found in cancer, but how tumor cells drive T-cell exhaustion remains elusive. Here, we find T-cell exhaustion linked to overall survival in 675 hepatocellular carcinoma (HCC) patients with diverse ethnicities and etiologies....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hung, Man Hsin, Lee, Joo Sang, Ma, Chi, Diggs, Laurence P., Heinrich, Sophia, Chang, Ching Wen, Ma, Lichun, Forgues, Marshonna, Budhu, Anuradha, Chaisaingmongkol, Jittiporn, Ruchirawat, Mathuros, Ruppin, Eytan, Greten, Tim F., Wang, Xin Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935900/
https://ncbi.nlm.nih.gov/pubmed/33674593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21804-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados