Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ

Pseudokinases are considered to be the inactive counterparts of conventional protein kinases and comprise approximately 10% of the human and mouse kinomes. Here, we report the crystal structure of the Legionella pneumophila effector protein, SidJ, in complex with the eukaryotic Ca(2+)-binding regula...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Sulpizio, Alan, Minelli, Marena E, Wan, Min, Burrowes, Paul D, Wu, Xiaochun, Sanford, Ethan J, Shin, Jung-Ho, Williams, Byron C, Goldberg, Michael L, Smolka, Marcus B, Mao, Yuxin
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Structural Biology and Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858067/
https://ncbi.nlm.nih.gov/pubmed/31682223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51162
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