GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126

Mutations in the transcription factor GATA2 cause lymphedema. GATA2 is necessary for the development of lymphatic valves and lymphovenous valves, and for the patterning of lymphatic vessels. Here, we report that GATA2 is not necessary for valvular endothelial cell (VEC) differentiation. Instead, GAT...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Development
मुख्य लेखकों: Mahamud, Md. Riaj, Geng, Xin, Ho, Yen-Chun, Cha, Boksik, Kim, Yuenhee, Ma, Jing, Chen, Lijuan, Myers, Greggory, Camper, Sally, Mustacich, Debbie, Witte, Marlys, Choi, Dongwon, Hong, Young-Kwon, Chen, Hong, Varshney, Gaurav, Engel, James Douglas, Wang, Shusheng, Kim, Tae-Hoon, Lim, Kim-Chew, Srinivasan, R. Sathish
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Company of Biologists Ltd 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857586/
https://ncbi.nlm.nih.gov/pubmed/31582413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.184218
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन