Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case

Anacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP) previously under development as a lipid‐modifying agent that reduces LDL‐cholesterol and increases HDL‐cholesterol in hypercholesterolemic patients. Anacetrapib demonstrates a long terminal half‐life and accumulates in adipose...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Johns, Douglas G., Wang, Sheng‐Ping, Rosa, Raymond, Hubert, James, Xu, Suoyu, Chen, Ying, Bateman, Thomas, Blaustein, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857080/
https://ncbi.nlm.nih.gov/pubmed/31832204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.543
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados