Bayesian Estimation of Three-Dimensional Chromosomal Structure from Single-Cell Hi-C Data

The problem of three-dimensional (3D) chromosome structure inference from Hi-C data sets is important and challenging. While bulk Hi-C data sets contain contact information derived from millions of cells and can capture major structural features shared by the majority of cells in the sample, they do...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Comput Biol
Hauptverfasser: Rosenthal, Michael, Bryner, Darshan, Huffer, Fred, Evans, Shane, Srivastava, Anuj, Neretti, Nicola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856950/
https://ncbi.nlm.nih.gov/pubmed/31211598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0100
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