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Reconstructing high-resolution chromosome three-dimensional structures by Hi-C complex networks

BACKGROUND: Hi-C data have been widely used to reconstruct chromosomal three-dimensional (3D) structures. One of the key limitations of Hi-C is the unclear relationship between spatial distance and the number of Hi-C contacts. Many methods used a fixed parameter when converting the number of Hi-C co...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Liu, Tong, Wang, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309071/
https://ncbi.nlm.nih.gov/pubmed/30591009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2464-z
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