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Chromosome3D: reconstructing three-dimensional chromosomal structures from Hi-C interaction frequency data using distance geometry simulated annealing

BACKGROUND: Reconstructing three-dimensional structures of chromosomes is useful for visualizing their shapes in a cell and interpreting their function. In this work, we reconstruct chromosomal structures from Hi-C data by translating contact counts in Hi-C data into Euclidean distances between chro...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Adhikari, Badri, Trieu, Tuan, Cheng, Jianlin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100196/
https://ncbi.nlm.nih.gov/pubmed/27821047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3210-4
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