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The three-dimensional organization of the genome in cellular senescence and age-associated diseases.

Recent advances in genomics and imaging technologies have increased our ability to interrogate the 3D conformation of chromosomes and to better understand principles of organization and dynamics, as well as how their alteration can lead to disease. In this review we describe how these technologies h...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Evans, Shane, Horrell, Jeremy, Neretti, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661233/
https://ncbi.nlm.nih.gov/pubmed/30031215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2018.07.022
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