A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

Pluripotent embryonic stem cells (ESCs) constitute an essential cellular niche sustained by epigenomic and transcriptional regulation. Any role of post-transcriptional processes remains less explored. Here, we identify a link between nuclear RNA levels, regulated by the poly(A) RNA exosome targeting...

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Publicat a:Cell Rep
Autors principals: Garland, William, Comet, Itys, Wu, Mengjun, Radzisheuskaya, Aliaksandra, Rib, Leonor, Vitting-Seerup, Kristoffer, Lloret-Llinares, Marta, Sandelin, Albin, Helin, Kristian, Jensen, Torben Heick
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856724/
https://ncbi.nlm.nih.gov/pubmed/31722198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.011
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