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Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids
Cystic fibrosis (CF) is a life-shortening genetic disease caused by mutations of CFTR, the gene encoding cystic fibrosis transmembrane conductance regulator. Despite considerable progress in CF therapies, targeting specific CFTR genotypes based on small molecules has been hindered because of the sub...
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| 出版年: | Drug Discov Today |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856431/ https://ncbi.nlm.nih.gov/pubmed/31173911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.05.029 |
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