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Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids
Cystic fibrosis (CF) is a life-shortening genetic disease caused by mutations of CFTR, the gene encoding cystic fibrosis transmembrane conductance regulator. Despite considerable progress in CF therapies, targeting specific CFTR genotypes based on small molecules has been hindered because of the sub...
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| Publicat a: | Drug Discov Today |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856431/ https://ncbi.nlm.nih.gov/pubmed/31173911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.05.029 |
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