Inflammatory Stimuli Trigger Increased Androgen Production and Shifts in Gene Expression in Theca-Interstitial Cells

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by theca cell hyperplasia and excessive androgen production. An increasing body of evidence has pointed to a close association between PCOS and low-grade chronic systemic inflammation. However, the mechanistic...

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Publicat a:Endocrinology
Autors principals: Fox, Chelsea W, Zhang, Lingzhi, Sohni, Abhishek, Doblado, Manuel, Wilkinson, Miles F, Chang, R Jeffrey, Duleba, Antoni J
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855291/
https://ncbi.nlm.nih.gov/pubmed/31599939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00588
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