A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection

Human cytomegalovirus (HCMV) can cause congenital infections, which are a leading cause of childhood disabilities. Since the rate of maternal-fetal transmission is much lower in naturally infected (HCMV-seropositive) women, we hypothesize that a vaccine candidate capable of eliciting immune response...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Liu, Yaping, Freed, Daniel C., Li, Leike, Tang, Aimin, Li, Fengsheng, Murray, Edward M., Adler, Stuart P., McVoy, Michael A., Rupp, Richard E., Barrett, Diane, Ye, Xiaohua, Zhang, Ningyan, Beck, Karen, Culp, Timothy, Das, Rituparna, Song, Liping, Vora, Kalpit, Zhu, Hua, Wang, Dai, Espeseth, Amy S., An, Zhiqiang, Musey, Luwy, Fu, Tong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854503/
https://ncbi.nlm.nih.gov/pubmed/31511385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00747-19
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