A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial

A conditionally replication-defective human cytomegalovirus (HCMV) vaccine, V160, was shown to be safe and immunogenic in a two-part, double-blind, randomized, placebo-controlled phase I clinical trial (NCT01986010). However, the specificities and functional properties of V160-elicited antibodies re...

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Pubblicato in:NPJ Vaccines
Autori principali: Li, Leike, Freed, Daniel C., Liu, Yaping, Li, Fengsheng, Barrett, Diane F., Xiong, Wei, Ye, Xiaohua, Adler, Stuart P., Rupp, Richard E., Wang, Dai, Zhang, Ningyan, Fu, Tong-Ming, An, Zhiqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172929/
https://ncbi.nlm.nih.gov/pubmed/34078915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00342-3
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