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Serine 229 Balances the Hepatitis C Virus Nonstructural Protein NS5A between Hypo- and Hyperphosphorylated States

The nonstructural protein NS5A of hepatitis C virus (HCV) is a phosphorylated protein that is indispensable for viral replication and assembly. We previously showed that NS5A undergoes sequential serine S232/S235/S238 phosphorylation resulting in NS5A transition from a hypo- to a hyperphosphorylated...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Tsai, Chia-Ni, Pan, Ting-Chun, Chiang, Cho-Han, Yu, Chun-Chiao, Su, Shih-Han, Yu, Ming-Jiun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854479/
https://ncbi.nlm.nih.gov/pubmed/31511391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01028-19
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