Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ITD AML

Fms‐like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations, common in pediatric acute myeloid leukemia (AML), associate with early relapse and poor prognosis. Past studies have suggested additional cooperative mutations are required for leukemogenesis in FLT3‐ITD+ AML. Using RNA s...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Buelow, Daelynn R., Pounds, Stanley B., Wang, Yong‐Dong, Shi, Lei, Li, Yongjin, Finkelstein, David, Shurtleff, Sheila, Neale, Geoffrey, Inaba, Hiroto, Ribeiro, Raul C., Palumbo, Reid, Garrison, Dominique, Orwick, Shelley J., Blachly, James S., Kroll, Karl, Byrd, John C., Gruber, Tanja A., Rubnitz, Jeffrey E., Baker, Sharyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853146/
https://ncbi.nlm.nih.gov/pubmed/31350825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12669
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