Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is characterised by an increase in mean pulmonary arterial pressure which almost invariably leads to right heart failure and premature death. More than 70% of familial PAH and 20% of idiopathic PAH patients carry heterozygous mutations in the bone morphogenetic...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Gomez‐Puerto, Maria Catalina, van Zuijen, Iris, Huang, Christopher JZ, Szulcek, Robert, Pan, Xiaoke, van Dinther, Maarten AH, Kurakula, Kondababu, Wiesmeijer, Catharina C, Goumans, Marie‐Jose, Bogaard, Harm‐Jan, Morrell, Nicholas W, Rana, Amer Ahmed, ten Dijke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852495/
https://ncbi.nlm.nih.gov/pubmed/31257577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5322
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