MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by obstructed pulmonary vasculatures. Current therapies for PAH are limited and only alleviate symptoms. Reduced levels of BMPR2 are associated with PAH pathophysiology. Moreover, reactive oxygen species, inflammation...

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Pubblicato in:Int J Mol Sci
Autori principali: Gomez-Puerto, Maria Catalina, Sun, Xiao-Qing, Schalij, Ingrid, Orriols, Mar, Pan, Xiaoke, Szulcek, Robert, Goumans, Marie-José, Bogaard, Harm-Jan, Zhou, Qian, ten Dijke, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312610/
https://ncbi.nlm.nih.gov/pubmed/32531895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114130
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