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Facile removal of 4-methoxybenzyl protecting group from selenocysteine

Historically, methods to remove the 4-methoxybenzyl (Mob) protecting group from selenocysteine (Sec) in peptides have used harsh and toxic reagents. The use of 2,2’- dithiobis-5-nitropyridine (DTNP) is an improvement over these methods, however many wash steps are required to remove the by-product c...

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Bibliographic Details
Published in:J Pept Sci
Main Authors: Jenny, Kaelyn A., Ste. Marie, Emma J., Mose, Gracyn, Ruggles, Erik L., Hondal, Robert J.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851407/
https://ncbi.nlm.nih.gov/pubmed/31410953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.3209
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