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Removal of The 5-Nitro-2-Pyridine-Sulfenyl Protecting Group From Selenocysteine and Cysteine by Ascorbolysis()

We previously reported on a method for the facile removal of 4-methoxybenzyl (Mob) and acetamidomethyl (Acm) protecting groups from cysteine (Cys) and selenocysteine (Sec) using 2,2′-dithiobis-5-nitropyridine (DTNP) dissolved in trifluoroacetic acid (TFA) (DTNP/TFA), with or without thioanisole. The...

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Bibliographic Details
Published in:J Pept Sci
Main Authors: SteMarie, Emma J., Ruggles, Erik L., Hondal, Robert J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098394/
https://ncbi.nlm.nih.gov/pubmed/27480992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2908
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