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Reduction of cysteine-S-protecting groups by triisopropylsilane(†)

Triisopropylsilane (TIS), a hindered hydrosilane, has long been utilized as a cation scavenger for the removal of amino acid protecting groups during peptide synthesis. However, its ability to actively remove S-protecting groups by serving as a reductant has largely been mischaracterized by the pept...

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Detalhes bibliográficos
Publicado no:J Pept Sci
Main Authors: Ste.Marie, Emma J., Hondal, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773273/
https://ncbi.nlm.nih.gov/pubmed/30353614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.3130
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