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Binding-induced folding under unfolding conditions: Switching between induced fit and conformational selection mechanisms

The chemistry of protein–ligand binding is the basis of virtually every biological process. Ligand binding can be essential for a protein to function in the cell by stabilizing or altering the conformation of a protein, particularly for partially or completely unstructured proteins. However, the mec...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Sen, Sreemantee, Udgaonkar, Jayant B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851327/
https://ncbi.nlm.nih.gov/pubmed/31582563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009742
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