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The Polypeptide Binding Conformation of Calreticulin Facilitates Its Cell-surface Expression under Conditions of Endoplasmic Reticulum Stress

We define two classes of calreticulin mutants that retain glycan binding activity; those that display enhanced or reduced polypeptide-specific chaperone activity, due to conformational effects. Under normal conditions, neither set of mutants significantly impacts the ability of calreticulin to media...

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Bibliografiset tiedot
Päätekijät: Jeffery, Elise, Peters, Larry Robert, Raghavan, Malini
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024734/
https://ncbi.nlm.nih.gov/pubmed/21075854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.180877
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