ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, due in part to the propensity of lung cancer to metastasize. Aberrant epithelial-to-mesenchymal transition (EMT) is a proposed model for the initiation of metastasis. During EMT cell-cell adhesion is reduced a...

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Publicado no:Nat Commun
Main Authors: Manshouri, Roxsan, Coyaud, Etienne, Kundu, Samrat T., Peng, David H., Stratton, Sabrina A., Alton, Kendra, Bajaj, Rakhee, Fradette, Jared J., Minelli, Rosalba, Peoples, Michael D., Carugo, Alessandro, Chen, Fengju, Bristow, Christopher, Kovacs, Jeffrey J., Barton, Michelle C., Heffernan, Tim, Creighton, Chad J., Raught, Brian, Gibbons, Don L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851102/
https://ncbi.nlm.nih.gov/pubmed/31719531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12832-z
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