Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination

The mechanisms that coordinate and balance a complex network of opposing regulators to control Schwann cell (SC) differentiation remain elusive. Here we demonstrate that zinc-finger E-box binding-homeobox 2 (Zeb2/Sip1) transcription factor is a critical intrinsic timer that controls the onset of Sch...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Wu, Lai Man Natalie, Wang, Jincheng, Conidi, Andrea, Zhao, Chuntao, Wang, Haibo, Ford, Zachary, Zhang, Liguo, Zweier, Christiane, Ayee, Brian G., Maurel, Patrice, Zwijsen, An, Chan, Jonah R., Jankowski, Michael P., Huylebroeck, Danny, Lu, Q. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961522/
https://ncbi.nlm.nih.gov/pubmed/27294509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4322
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