Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination

The mechanisms that coordinate and balance a complex network of opposing regulators to control Schwann cell (SC) differentiation remain elusive. Here we demonstrate that zinc-finger E-box binding-homeobox 2 (Zeb2/Sip1) transcription factor is a critical intrinsic timer that controls the onset of Sch...

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Publicado en:Nat Neurosci
Main Authors: Wu, Lai Man Natalie, Wang, Jincheng, Conidi, Andrea, Zhao, Chuntao, Wang, Haibo, Ford, Zachary, Zhang, Liguo, Zweier, Christiane, Ayee, Brian G., Maurel, Patrice, Zwijsen, An, Chan, Jonah R., Jankowski, Michael P., Huylebroeck, Danny, Lu, Q. Richard
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961522/
https://ncbi.nlm.nih.gov/pubmed/27294509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4322
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