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Structure-based inhibitors of amyloid beta core suggest a common interface with tau
Alzheimer’s disease (AD) pathology is characterized by plaques of amyloid beta (Aβ) and neurofibrillary tangles of tau. Aβ aggregation is thought to occur at early stages of the disease, and ultimately gives way to the formation of tau tangles which track with cognitive decline in humans. Here, we r...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6850776/ https://ncbi.nlm.nih.gov/pubmed/31612856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46924 |
| תגים: |
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