Neutrophil GM‐CSF receptor dynamics in acute lung injury

GM‐CSF is important in regulating acute, persistent neutrophilic inflammation in certain settings, including lung injury. Ligand binding induces rapid internalization of the GM‐CSF receptor (GM‐CSFRα) complex, a process essential for signaling. Whereas GM‐CSF controls many aspects of neutrophil biol...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: De Alessandris, Silvia, Ferguson, G. John, Dodd, Alison J., Juss, Jatinder K., Devaprasad, Abhinandan, Piper, Siân, Wyatt, Owen, Killick, Helen, Corkill, Dominic J., Cohen, E. Suzanne, Pandit, Aridaman, Radstake, Timothy R.D.J., Simmonds, Rosalind, Condliffe, Alison M., Sleeman, Matthew A., Cowburn, Andrew S., Finch, Donna K., Chilvers, Edwin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
NEUTROPHIL 2018, Quebec City, Canada, June 2–6 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850700/
https://ncbi.nlm.nih.gov/pubmed/30942918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MA0918-347R
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