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CXCL4 suppresses tolerogenic immune signature of monocyte‐derived dendritic cells
RNA sequencing and DNA methylomic profiling were performed after differentiating monocytes for 6 days into moDCs with/without CXCL4 presence. We show that CXCL4 downregulates genes associated with tolerogenicity in DCs including C1Q. Expression profiles of C1Q genes were negatively correlated with t...
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Publicado no: | Eur J Immunol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586983/ https://ncbi.nlm.nih.gov/pubmed/32502279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948341 |
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