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Drug repurposing for Dravet syndrome in scn1Lab (−/−) mutant zebrafish

Dravet syndrome (DS) is a severe genetic epileptic encephalopathy with onset during the first year of life. Zebrafish models recapitulating human diseases are often used as drug discovery platforms, but also for drug repurposing testing. It was recently shown that pharmacological modulation of three...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Sourbron, Jo, Partoens, Michèle, Scheldeman, Chloë, Zhang, Yifan, Lagae, Lieven, de Witte, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850687/
https://ncbi.nlm.nih.gov/pubmed/30663052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14647
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