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Drug repurposing for Dravet syndrome in scn1Lab (−/−) mutant zebrafish

Dravet syndrome (DS) is a severe genetic epileptic encephalopathy with onset during the first year of life. Zebrafish models recapitulating human diseases are often used as drug discovery platforms, but also for drug repurposing testing. It was recently shown that pharmacological modulation of three...

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書目詳細資料
發表在:Epilepsia
Main Authors: Sourbron, Jo, Partoens, Michèle, Scheldeman, Chloë, Zhang, Yifan, Lagae, Lieven, de Witte, Peter
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850687/
https://ncbi.nlm.nih.gov/pubmed/30663052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14647
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