Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte

Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...

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Bibliographic Details
Published in:Stem Cells
Main Authors: Shi, Xiaojie, Xiao, Zipei, Zonta, Francesco, Wang, Wei, Wan, Yue, Li, Yu, Wang, Nan, Kuang, Yuanyuan, Du, Mingjuan, Dong, Jian, Wang, Ju, Yang, Guang
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2019
Subjects:
Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850183/
https://ncbi.nlm.nih.gov/pubmed/30805989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2994
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