Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte

Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...

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Pubblicato in:Stem Cells
Autori principali: Shi, Xiaojie, Xiao, Zipei, Zonta, Francesco, Wang, Wei, Wan, Yue, Li, Yu, Wang, Nan, Kuang, Yuanyuan, Du, Mingjuan, Dong, Jian, Wang, Ju, Yang, Guang
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850183/
https://ncbi.nlm.nih.gov/pubmed/30805989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2994
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