Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte

Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...

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發表在:Stem Cells
Main Authors: Shi, Xiaojie, Xiao, Zipei, Zonta, Francesco, Wang, Wei, Wan, Yue, Li, Yu, Wang, Nan, Kuang, Yuanyuan, Du, Mingjuan, Dong, Jian, Wang, Ju, Yang, Guang
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Inc. 2019
主題:
Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850183/
https://ncbi.nlm.nih.gov/pubmed/30805989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2994
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