Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte

Remodeling of the gene regulatory network in cells is believed to be a prerequisite for their lineage reprogramming. However, its key regulatory factors are not yet elucidated. In this article, we investigate the role of PIWI proteins and provide evidence that one of them, MIWI2, is elicited during...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Shi, Xiaojie, Xiao, Zipei, Zonta, Francesco, Wang, Wei, Wan, Yue, Li, Yu, Wang, Nan, Kuang, Yuanyuan, Du, Mingjuan, Dong, Jian, Wang, Ju, Yang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850183/
https://ncbi.nlm.nih.gov/pubmed/30805989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2994
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