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Synthesis of γ-substituted carbonyl compounds from DMSO-mediated oxidation of enynamides: mechanistic insights and carbon- and hetero-functionalizations

Oxidative coupling of 1,3-enynamides using DMSO as a terminal oxidant has been developed. Carbon as well as unmodified heteroatom nucleophiles, including aliphatic alcohols, thiols, and hydrazides, could be efficiently alkylated at the γ-position in a highly regioselective fashion. The kinetic analy...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Chem Sci
Main Authors: Nguyen, Quynh H., Nguyen, Nguyen H., Kim, Hanbyul, Shin, Seunghoon
פורמט: Artigo
שפה:Inglês
יצא לאור: Royal Society of Chemistry 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849631/
https://ncbi.nlm.nih.gov/pubmed/31803452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03663f
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