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Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma

Background: Activation of telomere maintenance mechanisms (TMMs) is a hallmark of most cancers, and is required to prevent genome instability and to establish cellular immortality through reconstitution of capping of chromosome ends. TMM depends on the cancer type. Comparative studies linking tumor...

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Publicat a:Front Oncol
Autors principals: Nersisyan, Lilit, Hopp, Lydia, Loeffler-Wirth, Henry, Galle, Jörg, Loeffler, Markus, Arakelyan, Arsen, Binder, Hans
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848383/
https://ncbi.nlm.nih.gov/pubmed/31750255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01172
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