Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma

Background: Activation of telomere maintenance mechanisms (TMMs) is a hallmark of most cancers, and is required to prevent genome instability and to establish cellular immortality through reconstitution of capping of chromosome ends. TMM depends on the cancer type. Comparative studies linking tumor...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Nersisyan, Lilit, Hopp, Lydia, Loeffler-Wirth, Henry, Galle, Jörg, Loeffler, Markus, Arakelyan, Arsen, Binder, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848383/
https://ncbi.nlm.nih.gov/pubmed/31750255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01172
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