Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma

Background: Activation of telomere maintenance mechanisms (TMMs) is a hallmark of most cancers, and is required to prevent genome instability and to establish cellular immortality through reconstitution of capping of chromosome ends. TMM depends on the cancer type. Comparative studies linking tumor...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Nersisyan, Lilit, Hopp, Lydia, Loeffler-Wirth, Henry, Galle, Jörg, Loeffler, Markus, Arakelyan, Arsen, Binder, Hans
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848383/
https://ncbi.nlm.nih.gov/pubmed/31750255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01172
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