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Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells
Clinical use of olanzapine frequently causes severe hyperglycemia as an adverse effect. In this study, we elucidated mechanisms by which olanzapine reduced insulin secretion using the hamster pancreatic β-cell line HIT-T15. Reverse transcriptional-PCR analysis revealed expression of dopamine (D(2),...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6848069/ https://ncbi.nlm.nih.gov/pubmed/31712714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52590-y |
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